肿瘤分子学分析：英文版

肿瘤分子学分析：英文版
作　者： 美Jacqueline Boultwood 美Carrie Fidler
出版社： 世界图书出版西安公司
丛编项： 英文
版权说明： 本书为公共版权或经版权方授权，请支持正版图书
标　签： 预防医学
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作者简介

暂缺《肿瘤分子学分析：英文版》作者简介

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Over the past 20 years， technological advances in molecular biology haveproven invaluable to the understanding of the pathogenesis of human cancer.The application of molecular technology to the study of cancer has not onlyled to advances in tumor diagnosis， but has also provided markers for theassessment of prognosis and disease progression. The aim of Molecular Analysisof Cancer is to provide a comprehensive collection of the most up-to-datetechniques for the detection of molecular changes in human cancer. Leadingresearchers in the field have contributed chapters detailing practical proceduresfor a wide range of state-of-the-art techniques.Molecular Analysis of Cancer includes chapters describing techniquesfor the identification of chromosomal abnormalities and comprising： fluorescentin situ hybridization （FISH）， spectral karyotyping （SKY）， comparativegenomic hybridization （CGH）， and microsatellite analysis. FISH has a prominentrole in the molecular analysis of cancer and can be used for the detectionof ...

图书目录

ContentsPreface

...............................................................................................................

vContributors

.......................................................................................................

ix1

Molecular

Analysis

of

Cancer:

An

OverviewKen

Mills

.................................................................................................

Detection

of

Chromosome

Abnormalities

in

Leukemia

UsingFluorescence

In

Situ

HybridizationLyndal

Kearney,

Sabrina

Tosi,

and

Rina

J.

Jaju................................

Spectral

Karyotyping

in

Cancer

CytogeneticsEva

Hilgenfeld,

Cristina

Montagna,

Hesed

Padilla-Nash,Linda

Stapleton,

Kerstin

Heselmeyer-Haddad,and

Thomas

Ried

............................................................................

Comparative

Genomic

Hybridization

AnalysisBinaifer

R.

Balsara,

Jianming

Pei,

and

Joseph

R.

Testa

................

Detection

of

Chromosomal

Deletions

by

Microsatellite

AnalysisRachel

E.

Ibbotson

and

Martin

M.

Corcoran

....................................

Detection

and

Quantification

of

Leukemia-Specific

RearrangementsAndreas

Hochhaus

..............................................................................

Detection

of

t(2;5)(p23;q35)

Translocation

by

Long-Range

PCRof

Genomic

DNAYunfang

Jiang,

L.

Jeffrey

Medeiros,

and

Andreas

H.

Sarris..........

Use

of

DNA

Fingerprinting

to

Detect

Genetic

Rearrangementsin

Human

CancerVorapan

Sirivatanauksorn,

Yongyut

Sirivatanauksorn,Arthur

B.

McKie,

and

Nicholas

R.

Lemoine

...............................

Mutation

Analysis

of

Large

Genomic

Regions

in

Tumor

DNA

UsingSingle-Strand

Conformation

Polymorphism:

Lessons

fromthe

ATM

GeneIgor

Vorechovsky

...............................................................................

Mutational

Analysis

of

Oncogenes

and

Tumor

Suppressor

Genesin

Human

Cancer

Using

Denaturing

Gradient

Gel

ElectrophoresisPer

Guldberg,

Kirsten

Grønbæk,

Jesper

Worm,

Per

thor

Straten,and

Jesper

Zeuthen

..........................................................................

125viiviii

Contents11

Detection

of

Mutations

in

Human

Cancer

Using

NonisotopicRNase

Cleavage

AssayMarianna

Goldrick

and

James

Prescott

.........................................

Mutational

Analysis

of

the

Neurofibromatosis

Type

Genein

Childhood

Myelodysplastic

Syndromes

Using

a

ProteinTruncation

AssayLucy

Side

............................................................................................

Mutation

Analysis

of

Cancer

Using

Automated

SequencingAmanda

Strickson

and

Carrie

Fidler

...............................................

Detection

of

Differentially

Expressed

Genes

in

Cancer

UsingDifferential

DisplayYineng

Fu

............................................................................................

Genomewide

Gene

Expression

Analysis

Using

cDNA

MicroarraysChuang

Fong

Kong

and

David

Bowtell...........................................

Gene

Expression

Profiling

in

Cancer

Using

cDNA

MicroarraysJaved

Khan,

Lao

H.

Saal,

Michael

L.

Bittner,

Yuan

Jiang,Gerald

C.

Gooden,

Arthur

A.

Glatfelter,

and

Paul

S.

Meltzer

.....

Wilms

Tumor

Gene

WT1

as

a

Tumor

Marker

for

Leukemic

Blast

Cellsand

Its

Role

in

LeukemogenesisHaruo

Sugiyama.................................................................................

Detection

of

Aberrant

Methylation

of

the

p15INK4B

Gene

PromoterToshiki

Uchida

...................................................................................

Clonality

Studies

in

Cancer

Based

on

X

Chromosome

InactivationPhenomenonJohn

T.

Phelan

II

and

Josef

T.

Prchal

.............................................

Telomere

Length

Changes

in

Human

CancerDominique

Broccoli

and

Andrew

K.

Godwin

.................................

Measurement

of

Telomerase

Activity

in

Human

Hematopoietic

Cellsand

Neoplastic

DisordersKazuma

Ohyashiki

and

Junko

H.

Ohyashiki

..................................

279Index

............................................................................................................