Rudolph儿科学（第22版 英文版）

Contributors

Preface

Acknowledgments

SECTION 1:FUNDAMENTALS OF PEDIATRICS

SECTION 2: HEALTHPROMOTION AND DISEASE PREVENTION

Part 1: HealthMaintenance Issues

Part 2: ManagingFamily Transition

SECTION 3: NUTRITION

SECTION 4: ABUSE,NEGLECT, VIOLENCE

SECTION 5: NEWBORN

Part 1: Care of theNewborn

Part 2: Infants atRisk

Part 3: SpecificNeonatal Conditions

Part 4: DisordersSpecifically Related to Preterm Birth

SECTION 6: PRINCIPLESOF ADOLESCENT CARE

Part 1: Growth andDevelopment

Part 2: HealthProblems of Adolescents

Part 3: Mental HealthDisorders in the Adolescent

Part 4: ReproductiveHealth Problems

SECTION 7:DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Part 1: GeneralConcepts

Part 2: DevelopmentalVariation to Disorder

Part 3: MajorPsychopathologic Disorders

Part 4: PsychosocialContext of Development and Behavior

SECTION 8: THE ACUTELYILL INFANT AND CHILD

Part 1: Assessment ofthe Acutely Ill Infant and Child

Part 2: Stabilizationand Management of the Acutely Ill Infant and Child

Part 3: Injuries andUntoward Events

SECTION 9: THECHRONICALLY ILL INFANT AND CHILD

Part 1: The ChangingOutlook of Chronic Illness in Childhood

Part 2: Death andDying in Childhood

SECTION 10:TRANSPLANTATION

SECTION 11: INHERITEDDISORDERS OF METABOLISM

Part 1: Inborn Errorsof Metabolism

Part 2: Disorders ofAmino Acid (AA) and Organic Acid (OA) Metabolism

Part 3: Inborn Errorsof Water Soluble Vitamins

146. Introduction, Stephen I. Goodman

147.Vitamin B12 and Folic Acid, David Watkins and David S.Rosenblatt

148.Biotin Responsive Disorders, Stephen I. Goodman

149. Vitamin B6 and Vitamin B1 ResponsiveDisorders, Jean-MarieSaudubray

Part 4: Disorders ofFatty Acid Oxidation, Ketogenesis, and Ketolysis

150. Disorders of Fatty Acid Oxidation, Stephen I. Goodman

151.Disorders of Ketogenesis, Stephen I. Goodman

152. Disorders of Ketolysis, Stephen I. Goodman

Part 5: CarbohydrateMetabolism

Part 6: Disorders ofOxidative Phosphorylation and Pyruvate Oxidation

Part 7: OrganelleRelated Disorders

Part 8: Disorders ofLipid and Bile Acid Metabolism

Part 9: Disorders ofNucleic Acids, Heme Metabolism, and Metals Transport

SECTION 12: CLINICALGENETICS AND DYSMORPHOLOGY

Part 1: The GeneticApproach to Disorders of Children

Part 2: ChromosomalDisorders

Part 3: Birth Defects,Malformations, and Syndromes

SECTION 13:IMMUNOLOGIC DISORDERS

SECTION 14: ALLERGICDISORDERS

SECTION 15:RHEUMATOLOGY

Part 1: GeneralPrinciples in Rheumatology

Part 2: SpecificRheumatologic Disorders

Part 3: Systemic Syndromesin Rheumatology

SECTION 16: THEMUSCULOSKELETAL SYSTEM

SECTION 17: INFECTIOUSDISEASES

Part 1: Principles ofInfectious Disease

Part 2: Infections ofOrgan Systems

Part 3: Infections ofthe Respiratory System

Part 4: Treatment andPrevention of Infectious Diseases

Part 5: BacterialInfections

Part 6: FungalInfections

Part 7: ViralInfections

Part 8: ParasiticInfections--Nematodes

Part 9: ParasiticInfections--Trematodes

Part 10: ParasiticInfections--Protozoa

SECTION 18: DISORDERSOF THE SKIN

SECTION 19: DISORDERSOF THE EAR, NOSE, AND THROAT

SECTION 20: DISORDERSOF THE ORAL CAVITY

SECTION 21: DISORDERSOF THE GASTROINTESTINAL TRACT

Part 1: PresentingSigns and Symptoms

Part 2: EsophagealDisorders

Part 3: Congenital andAnatomic Disorders of the Stomach and Intestine

Part 4: Disorders ofDigestion and Absorption

Part 5: Disorders ofthe Stomach and Intestine

Part 6: The ExocrinePancreas

SECTION 22: DISORDERSOF THE LIVER AND BILIARY TRACT

SECTION 23: DISORDERSOF THE BLOOD

Part 1: Principles ofBlood Disorders

Part 2: Disorders ofRed Blood Cells and Anemia

Part 3: Disorders ofCoagulation and Platelets

Part 4: Disorders ofthe Spleen and Lymph Nodes

Part 5: Disorders ofWhite Blood Cells,

Part 6: Principles ofTransfusion

SECTION 24: NEOPLASTICDISORDERS

Part 1: Principles ofOncology

Part 2: HematologicMalignancies

Part 3: Solid Tumors

Part 4: MononuclearPhagocytic System Disorders

SECTION 25: DISORDERSOF THE KIDNEY AND URINARY TRACT

Part 1: Principles ofNephrology

Part 2: Abnormalitiesof the Kidney and Urinary Tract

SECTION 26: DISORDERSOF THE CARDIOVASCULAR SYSTEM

Part 1: Principles ofCardiology

Part 2: Approach tothe Patient with Cardiovascular Disease

Part 3: AcquiredCardiovascular Disease

Part 4: DiagnosticTools in Heart Disease

Part 5: Management ofPatients with Cardiovascular Disease

SECTION 27: DISORDERSOF THE RESPIRATORY SYSTEM

Part 1: Principles ofPulmonology

Part 2: Disorders ofthe Respiratory System

SECTION 28: DISORDERSOF THE ENDOCRINE SYSTEM

SECTION 29: DISORDERSOF THE NERVOUS SYSTEM

Part 1: Principles ofNeurology

Part 2: AbnormalDevelopment of the Nervous System

Part 3: AcuteDeterioration of Neurologic Function

Part 4: Epilepsy

Part 5: ParoxysmalDisorders

Part 6: Disorders ofStrength, Tone, and Sensation

Part 7: DevelopmentalDelay and Regression

SECTION 30: DISORDERS OF THE EYES

Part 1: General Principles

Part 2: Disorders of the Eye

Index v 目 录Contributors

Preface

Acknowledgments

SECTION 1: FUNDAMENTALS OF PEDIATRICS

Section Editor: Thomas G. DeWitt

1. Role of the Pediatrician, Thomas G. DeWitt and Neal Halfon

2. Decision-Making: Use of Evidence-BasedMedicine, Suresh Nagappan andKenneth B. Roberts

3. Communication, Elizabeth A. Rider

4.Interviewing Techniques, Christopher F. Bolling

5.Systems of Practice and Office Management, Peter Margolis

6.Core Competencies, Theodore C. Sectish

7.Patient and Family-Centered Care, Jeffrey M. Simmons, Stephen E.Muething, and Kathleen L. Dressman

8.Disaster Preparedness, Janet M. Berreman and Linda Rudolph

9. Law, Ethics, and Clinical Judgment, Angela Roddey Holder

SECTION 2: HEALTH PROMOTION AND DISEASEPREVENTION

Section Editor: Eve R. Colson

Part 1: Health Maintenance Issues

10. Well-Child Care, Judith S. Shaw and Judith S.Palfrey

11.Child Development, IlgiOzturkErtem and Carol CohenWeitzman

12.Screening, AdaM. Fenick

13.Oral Heatlh Supervision, Ada M. Fenick and Linda P. Nelson

14.Complementary and Alternative Medicine (CAM), AnjuSawni

15.Culture and Pediatric Practice, SakenaAbedin

16.Gay and Lesbian Parents, Cindy M. Schorzman and Melanie A.Gold

17. Environmental Pediatrics, Ruth A. Etzel

18. Travel Medicine, Joseph A. Zenel and Chandy C. John

Part 2: Managing Family Transition

19. Family Function and Birth of a Child, William I. Cohen

20.Foster Care and Adoption, Brad D. Berman and Carol CohenWeitzman

21.Family Discord and Divorce, Michael Jellinek

22. Supporting the Grieving Child and Family, David J. Schonfeld

SECTION 3: NUTRITION

Section Editor: Praveen S. Goday

23. Normal Nutritional Requirements, Praveen S. Goday

24.Breast-Feeding, Jane Morton and Ruth A. Lawrence

25.Infant Formula and Complementary Foods, Margaret Kirby

26.Postdischarge Nutritional Management of thePremature Infant, Utpala G.Das

27. Nutritional Issues: Toddler to Adolescent, Margaret Kirby and Praveen S. Goday

28. Assessment of Nutritional Adequacy, Praveen S. Goday

29.Malnutrition and Refeeding, Praveen S. Goday

30.Poor Weight Gain, Karen A. Francolla and Praveen S.Goday

31. Approach to the Infant and Child withFeeding Difficulty, Richard J.Noel

32. The Overweight or Obese Child, Michelle Smith-Beckley and Brian M.Fidlin

33. Specialized Nutrition Support, Praveen S. Goday

34. Nutritional Access Devices, Lillian Sablan and Karen Sherry

SECTION 4: ABUSE, NEGLECT, VIOLENCE

Section Editor: John M. Leventhal

35. Child Maltreatment: Neglect to Abuse, John M. Leventhal and Andrea G.Asnes

36. Family and Community Violence, Renée Boynton-Jarrett and RobertSege

37. Child Abuse Prevention: What PediatriciansCan Do, Wendy Gwirtzman andHoward Dubowitz

SECTION 5: NEWBORN

Section Editors: Alan H. Jobe and James M.Greenberg

Part 1: Care of the Newborn

38. Historical Perspectives, James G. Greenberg

39.Care of the Fetus, Alan H. Jobe

40.Fetal Disorders, Timothy M. Crombleholme and Foong-YenLim

41.Neonatal Mortality and Morbidity, Avroy A. Fanaroff

42. Delivery Room Resuscitation, Myra H. Wyckoff

43. Transitional Changes in the Newborn, David P. Carlton

44.Examination of the Newborn Infant, Joseph A. Zeneel

45. Postnatal Care and Observation, Anthony E. Burgos

Part 2: Infants at Risk

46. Multiple Births, James M. Greenberg

47. The Small-for-Gestational Age Infant, William W. Hay, Jr.

48. Infant of a Diabetic Mother, Heather Morein French and RebeccaA. Simmons

Part 3: Specific Neonatal Conditions

49. Approach to the Cyanotic Infant, Robin H. Steinhorn

50. Abnormalities of the Lungs, M. Grisel Galarza and Ilene R.S.Sosenko

51. Metabolic Abnormalities, William W. Hay, Jr.

52. Brain Abnormalities and Injuries, SeethaShankaran and C. MichaelCotton

53. Hematologic Abnormalities and Jaundice, Henry C. Lee and AshimaMadan

Part 4: Disorders Specifically Related toPreterm Birth

54. Respiratory Distress Syndrome, Thomas N. Hansen and Samuel Hawgood

55.Patent DuctusArteriosus and DuctusVenosus, Ronald I. Clyman

56.Hemodynamics, Nick Evans

57.Necrotizing Enterocolitis, Barbara Warner

58.Intraventricular Hemorrhage, Henrietta S. Bada

59. Bronchopulmonary Dysplasia, Alan H. Jobe

60. Emergencies, James M. Greenberg

61. Special Intensive Care, Thomas A. Parker

62. Outcomes of Preterm and Term Infants, Marilee C. Allen

SECTION 6: PRINCIPLES OF ADOLESCENT CARE

Section Editors: Charles E. Irwin, Jr.,Mary-Ann Shafer, and Anna-Barbara Moscicki

Part 1: Growth and Development

63. Somatic Growth and Development, Charles E. Irwin, Jr.

64. Reproductive Growth and Development in theFemale Adolescent, MelissaSlivka, Anna-Barbara Moscicki, and Mary-Ann Shafer

65. Reproductive Growth and Development in theMale Adolescent, David J.Breland and Mark L. Rubinstein

66. Psychological Development, Elizabeth M. Ozer and Charles E.Irwin, Jr.

67. The Adolescent Visit, Charles E. Irwin, Jr.

Part 2: Health Problems of Adolescents

68. Mortality, ElizabethM. Ozer

69. Morbidity, CharlesE. Irwin, Jr.

70. Sexual Behavior, Erica B. Monasterio

71. Substance Use and Abuse, Stephanie N. Crewe and Arik V.Marcell

Part 3: Mental Health Disorders in theAdolescent

72. Depression, Anxiety, and Other Disorders, Kim Peter Norman

73. Disorders of Eating, Kim Peter Norman, Sara M. Buckelew,and Andrea K. Garber

Part 4: Reproductive Health Problems

74. Breast Masses, Jennifer C. Edman and Mary-AnnShafer

75.Scrotal Masses, David J. Breland and Mark L.Rubinstein

76.Menstrual Problems, Jennifer C. Edman and Mary-Ann Shafer

77.Intrauterine and Ectopic Pregnancy, Erica B. Monasterio and Mary-AnnShafer

78. Contraception, Erica B. Monasterio and Mary-AnnShafer

SECTION 7: DEVELOPMENTAL AND BEHAVIORALPEDIATRICS

Section Editor: Martin T. Stein

Part 1: General Concepts

79. Introduction to Developmental and BehavioralPediatrics, Martin T. Stein

80.Fundamental Concepts of Child Development, W. Thomas Boyce and Jack P.Shonkoff

81. Brain Development and Behavior, Charles A. Nelson III

82. Standardized Developmental Screening andAssessment Instruments, MartinT. Stein

Part 2: Developmental Variation to Disorder

83. Crying in Infants, Ronald G. Barr and Takeo Fujiwara

84.Hyperactivity and Inattention, Martin T. Stein and Michael I.Reiff

85. Learning Problems, Michael I. Reiff and Martin T.Stein

86. Language Delay, James S. Andrews and Heidi M.Feldman

87. Difficult Behavior, Martin T. Stein

88. Anxiety, DeniseA. Chavira

89.Repetitive Behaviors, Adrian D. Sandler

90. Gender Identity and Sexual Behavior, Kenneth J. Zucker

91. Developmental Delay, Nathan J. Blum

Part 3: Major Psychopathologic Disorders

92. Autistic Spectrum Disorders, Michael I. Reiff

93.Affective Disorders and Suicide, Laura Prager, Steven C. Schlozman,and Michael Jellinek

94.Pediatric Condition Falsification, Herbert Schreier

95. Childhood Schizophrenia, Fred R. Volkmar

Part 4: Psychosocial Context of Developmentand Behavior

96. Families in the 21st Century: AnIntroduction to Families, LaurieJ. Baumann and Ruth E. K. Stein

97. Nonparental Childcare, Nerissa S. Bauer

98.Vulnerable Child Syndrome, Yi Hui Liu

99.Adaptation to Illness, David J. Schonfeld

100.Poverty, Homelessness, and SocialDisorganization, Barry S.Zuckerman and Megan Sandel

101. Resiliency in Children and Adolescents, Saul Levine

SECTION 8: THE ACUTELY ILL INFANT AND CHILD

Section Editors: Julio Pérez Fontán andGeorge Lister

Part 1: Assessment of the Acutely Ill Infantand Child

102. Respiratory Distress and Failure, Julio Pérez Fontán

103. Decreased Perfusion and Circulatory Shock, George E. Lister

104. Acute Neurological Dysfunction, Susan T. Arnold

105. The Febrile Child, M. Douglas Baker and Jeffrey R.Avner

Part 2: Stabilization and Management of theAcutely Ill Infant and Child

106. Monitoring of Vital Function, George E. Lister

107.Vascular Access, Andreas A. Theodorou and Robert A.Berg

108. Cardiopulmonary Resuscitation, Mary Fran Hazinski

109. Life Support Systems, Julio Pérez Fontán

110.Stabilization and Transport, Deborah Lerner, George Lister, andJulio Pérez Fontán

111.Management of Cerebral Edema and ElevatedIntracranial Pressure, StevenG. Kernie

112. Perioperative Care, Desmond B. Henry

113. Pain Management and Sedation, Alan Farrow-Gillespie

114. Acute Metabolic Dysfunction, Ralph J. DeBerardinis

Part 3: Injuries and Untoward Events

115. Acute Inflammation, Clifford W. Bogue

116.Trauma, Burns, and Bites, Robert P. Foglia

117.Submersion Injury, Pamela J. Okada and M. DouglasBaker

118. Foreign-Body Aspiration, Margaret A. Kenna

119. Apparent Life-Threatening Events and SIDS, Michael J. Corwin

120. Toxic Ingestions and Exposures, Sing-Yi Feng, Collin S. Goto, andM. Douglas Baker

121. Heat Stress, Michael Apkon

122. Poisonous Bites and Stings, Dee Hodge III and Carl R. Baum

SECTION 9: THE CHRONICALLY ILL INFANT ANDCHILD

Section Editors: Julio Pérez Fontán andGeorge E. Lister

Part 1: The Changing Outlook of ChronicIllness in Childhood

123. Psychological and Behavioral Responses inChildren and Their Families, PatriciaJ. Hicks

124. The Technology-Dependent Child, John B. Gordon, Sarah P. Brown,Jerie Beth Karkos, and Lynn A. D'Andrea

Part 2: Death and Dying in Childhood

125. Caring for Children Dying From ChronicDisease, Arthur R. Ablin

126.Hospice and Palliative Care, Julie Hauer, Barbara L. Jones, andJoanne Wolfe

127. Law, Ethics, and Caring Near the End ofLife, Angela Roddey Holder

SECTION 10: TRANSPLANTATION

Section Editor: Patrick J. Healey

128. Pediatric Transplantation, Patrick J. Healey

129. Kidney Transplantation, Jodi M. Smith and Ruth A. McDonald

130. Liver Transplantation, Patrick J. Healey

131. Intestinal and Multivisceral Transplant, Simon Horslen

132. Heart Transplant, Beth D. Kaufman

133. Hematopoietic Cell Transplantation, Ann E. Woolfrey, Paul A. Carpenter,and Jean E. Sanders

SECTION 11: INHERITED DISORDERS OF METABOLISM

Section Editor: Jean-Marie Saudubray

Part 1: Inborn Errors of Metabolism

134. Principles of Inborn Errors of Metabolism, Jean-Marie Saudubray and Joe T.R.Clarke

Part 2: Disorders of Amino Acid (AA) andOrganic Acid (OA) Metabolism

135. Hyperphenylalaninemias, Bernd Christian Schwahn

136. Disorders of the Tyrosine Metabolism, Bernd Christian Schwahn

137.Disorders of the Branched Chain Amino andOrganic Acid Metabolism, StephenI. Goodman and Jean-Marie Saudubray

138.Disorders of Sulfur-Containing Amino AcidMeteabolism, Bernd ChristianSchwahn

139.Disorders of Glycine, Serine, and ProlineMetabolism, Bernd ChristianSchwahn

140.Disorders of Metabolism of Lysine,Hydrozylysine, and Related Compounds, StephenI. Goodman

141.Disorders of Metabolism of NeurotransmitterAmino Acids, JaakJaeken

142.Disorders of Creatine and OrnithineMetabolism, SylviaStockler-Ipsiroglu

143. Disorders of Amino Acid Transport AcrossCell Membranes, KirstiNäntö-Salonenand Ollie Simell

144. Other Disorders of Amino Acid Metabolism, Jean-Marie Saudubray

145. Urea Cycle and Related Disorders, Mendel Tuchman, UtaLichter-Konecki,and Mark L. Batshaw

Part 3: Inborn Errors of Water SolubleVitamins

146. Introduction, Stephen I. Goodman

147.Vitamin B12 and Folic Acid, David Watkins and David S.Rosenblatt

148.Biotin Responsive Disorders, Stephen I. Goodman

149. Vitamin B6 and Vitamin B1 ResponsiveDisorders, Jean-MarieSaudubray

Part 4: Disorders of Fatty Acid Oxidation,Ketogenesis, and Ketolysis

150. Disorders of Fatty Acid Oxidation, Stephen I. Goodman

151.Disorders of Ketogenesis, Stephen I. Goodman

152.Disorders of Ketolysis, Stephen I. Goodman

153. Disorders of Leukotriene Synthesis andFatty Aldehyde Dehydrogenase, StephenI. Goodman

Part 5: Carbohydrate Metabolism

154. Disorders of Glycogen Metabolism, Priya S. Kishnani and Yuan-TsongChen

155.Disorders of Galactose and FructoseMetabolism and Gluconeogenesis, PriyaS. Kishnani and Yuan-Tsong Chen

156.Disorders of Pentose Phosphate Pathway, Priya S. Kishnani and Yuan-TsongChen

157. Disorders of Glucose Transporters, René Santer

Part 6: Disorders of OxidativePhosphorylation and Pyruvate Oxidation

158. Respiratory Chain Disorders, Salvatore DiMauro

159. Disorders of Energy Metabolism, Juan M. Pascual and Salvatore DiMauro

Part 7: Organelle Related Disorders

160. Mucopolysaccharidosis, Glycoproteinosis,and Mucolipidosis, JamesEdmond Wraith

161. Sphingolipidoses, Joe T.R. Clarke

162. Peroxisomal Disorders, David Valle, Gerald V. Raymond, andStephen J. Gould

163. Congenital Disorders of Glycosylation, JaakJaeken

Part 8: Disorders of Lipid and Bile AcidMetabolism

164. Disorders of Cholesterol Synthesis, Peter T. Clayton

165.Disorders of Bile Acid Synthesis, Peter T. Clayton

166. Disorders of Lipid and Lipoprotein Metabolism, Peter O. Kwiterovich, Jr.

Part 9: Disorders of Nucleic Acids, HemeMetabolism, and Metals Transport

167. Disorders of Heme Biosynthesis: ThePorphyrias, Robert J. Desnick

168. Disorders of Purine and PyrimidineMetabolism, Georges van denBerghe

169. Disorders of Metal Metabolism, Jean-Marie Saudubray

SECTION 12: CLINICAL GENETICS ANDDYSMORPHOLOGY

Section Editors: John C. Carey and Michael J.Bamshad

Part 1: The Genetic Approach to Disorders ofChildren

170. Key Principles in Human Genetics, Michael J. Bamshad and Lynn B.Jorde

171. Multifactorial Inheritance, Lynn B. Jorde

172. Principles of Care, Claire O. Leonard

Part 2: Chromosomal Disorders

173. Human Cytogenetics, Sarah T. South and John C. Carey

174. Chromosome Disorders, John C. Carey

Part 3: Birth Defects, Malformations, andSyndromes

175. Birth Defects, Malformations, andSyndromes, John C. Carey andMichael J. Bamshad

176.Syndromes of Multiple CongenitalAnomalies/Dysplasias, John C.Carey

177.Craniofacial Disorders, Carrie Lyn Heike and Michael L.Cunningham

178. Approach to the Child with Birth Defects, John C. Carey and Michael J.Bamshad

179. Genetics Skeletal Disorders, John C. Carey and Michael J.Bamshad

180.Congenital Contractures, Michael J. Bamshad and John C.Carey

181.Connective Tissue Dysplasias, Alan Rope

182.Neurocutaneous Disorders, David H. Viskochil

183.Environmental Causes of Birth Defects, Elizabeth Balken, MarshaLeen-Mitchell, Lynn P. Martinez, and Julia A. Robertson

184.Disorders of Accelerated Aging, John C. Carey

185. Genetic Evaluation of DevelopmentalDelay/Mental Retardation, AgatinoBattagliaand John C. Carey

SECTION 13: IMMUNOLOGIC DISORDERS

Section Editor: Talal A. Chatila

186. Overview of the Immune System, Eli M. Eisenstein, Kathleen E.Sullivan, and Calvin B. Williams

187.Undue Susceptibility to Infection, Talal A. Chatila

188.Primary Immunodeficiencies, Talal A. Chatila

189. Complement Disorders, Patricia C. Giclas and Ashley A.Frazer-Abel

SECTION 14: ALLERGIC DISORDERS

190. Allergic Disease and Atopy, Talal A. Chatila

191.Clinical Aspects of Allergic Diseases, Maria Garcia-Lloret

192.Allergic Rhinitis and Conjunctivitis, Maria Garcia-Lloret

193.Anaphylaxis, Urticaria, and Angioedema, Marc A. Riedel

194. Food Allergy, Maria Garcia-Lloret

195. Insect Allergy, Maria Garcia-Lloret

196. Latex Allergy, Marc A. Riedel

197. Adverse Reactions to Drugs, Marc A. Riedel

SECTION 15: RHEUMATOLOGY

Section Editor: Robert P. Sundel

Part 1: General Principles in Rheumatology

198. Pathogenesis of Inflammatory and AutoimmuneDisorders, Kathleen E.Sullivan

199.History and Physical Exam, Robert P. Sundel

200. Diagnostic Testing in Rheumatology, Peter A. Nigrovic

Part 2: Specific Rheumatologic Disorders

201. Juvenile Idiopathic Arthritis, Carol A. Wallace, David A. Cabral,and Robert P. Sundel

202.Spondyloarthropathies, David A. Cabral and Lori B. Tucker

203.Vasculitides, Karyl S. Barron

204. Systemic Lupus Erythematosus, OverlapConnective Tissue Diseases, and Mixed Connective Tissue Disease, Earl D. Silverman

205. Juvenile Dermatomyositis, Lisa G. Rider

206. Scleroderma, Francesco Zulian

Part 3: Systemic Syndromes in Rheumatology

207. Musculoskeletal Pain Syndromes, Yukiko Kimura

208. Chronic Fatigue Syndrome, David S. Leslie

209. Autoinflammatory Disorders, Peter J. Hashkes

SECTION 16: THE MUSCULOSKELETAL SYSTEM

Section Editor: John A. Herring

210. Growth and Development, John G. Birch

211. The Limping Child, Lawson A.B. Copley

212. Torsional and Angular Deformities, Karl E. Rathjen

213.Disorders of the Foot, Charles E. Johnston

214.Disorders of the Knee, John A. Herring

215.Developmental Dysplasia of the Hip, David A. Podeszwa

216.Disorders of the Neck and Spine, Daniel J. Sucato

217.Disorders of the Upper Extremity, Marybeth Ezaki

218.Injuries, PhilipWilson

219.Tumors, B.Stephens Richards

220.Neuromuscular Disorders, Lori A. Karol

221. Common Orthopedia Misses, John A. Herring

SECTION 17: INFECTIOUS DISEASES

Section Editors: Anne A. Gershon and Peter J.Hotez

Part 1: Principles of Infectious Disease

222. Bacterial Pathogenesis, Janet R. Gilsdorf and Carl F. Marrs

223.Bacteremia, Sepsis, and Septic Shock, Stephanie H. Stovall and Richard F.Jacobs

224.Viral Pathogenesis, Anne Moscona and Anne A. Gershon

225. Infection Control, Margaret C. Fisher

226. Diagnostic Approaches for InfectiousDiseases, John C. Christensonand E. Kent Korgenski

227.Acute Fever without a Focus, Steven Black

228.Fever of Unknown Origin, Russell W. Steele

229.Fever and Infection in the ImmunocompromisedPatient, David B. Haslam andJeffrey Scott McKinney

230. Therapy for Perinatal and NeonatalInfections, David W.Kimberlin, Debra L. Palazzi, and Richard J. Whitley

Part 2: Infections of Organ Systems

231. Bacterial Infections of the Central NervousSystem, Thomas S. Murray andRobert S. Baltimore

232.Viral Infections of the Central NervousSystem, John F. Modlin

233.Sexually Transmitted Infections, Loris Y. Hwang, Anna-BarbaraMoscicki, and Mary-Ann Shafer

234.Bone, Joint, and Soft Tissue Infections, Robin B. Churchill and Blanca E.Gonzalez

235.Cardiac Infections, Janet A. Stockheim and Stanford T.Shulman

236.Gastrointestinal Infections, Matthew B. Laurens and Michael S.Donnenberg

237.Infections of the Liver, M. Kyle Jensen and GrzegorzTelega

238.Urinary Tract Infections, Keith M. Krasinski

239. Catheter-Associated Infections, Marc Foca

Part 3: Infections of the Respiratory System

240. Community-Acquired and Bacterial Pneumoniain Children, Stephen I. Pelton

241.Viral Respiratory Infections IncludingInfluenza, J. Robert Honeggerand Michael T. Brady

242.Fungal Respiratory Infections, Hana Hakim and Aditya H. Gaur

243. Infections of the Ear, Jerome O. Klein

Part 4: Treatment and Prevention ofInfectious Diseases

244. Immunizations, Kristina A. Bryant

245. Antiviral Therapy,David K. Hong andCharles G. Prober

246. Antibacterial Therapy, David K. Hong and Charles G. Prober

247. Antifungal Therapy, Patricia M. Flynn

Part 5: Bacterial Infections

248. Actinomycosis, Nahed Abdel-Haq and Ashir Kumar

249.Anaerobic Infections, Ayesha Mirza and Mobeen H. Rathore

250.Clostridial Infections, Jose Zayas and Mobeen H. Rathore

251.Anthrax (Bacillus anthracis), Denis Bratcher

252.Arcanobacterium, Dennis L. Murray

253. Bacilluscereus

254.Brucellosis, Ziad M. Shehab

255. Burkholderia and Pseudomonas, Jane L. Burns

256. campylobacter Infections, Guillermo M. Ruiz-Palacios

257. Cat Scratch Disease, Moshe Ephros and Michael Giladi

258.Chancroid (Hemophilusducreyi), Mary Allen Staat

259.Chlamydia, NavjyotK. Vidwan and Mary Allen Staat

260.Cholera, ChokechaiRongkavilitand Ashir Kumar

261.Diphtheria, Gary D. Overturf

262.Enterococci, Dwight A. Powell

263. Haemophilusinfluenzae, Mark R. Schleiss and Arnold L.Smith

264. Legionella Pneumonia, Lorry G. Rubin

265. Leptospirosis, Anne A. Gershon and Michael Katz

266.Listeriosis, Ziad M. Shehab

267. Lyme Disease, Michael A. Gerber

268. Moraxellacatarrhalis, Basim I.Asmar

269.Tuberculosis (Mycobacteria tuberculosis), Jeffrey R. Starke

270.Nontuberculous Mycobacterial Infections, Jeffrey R. Starke

271.Leprosy, WayneM. Meyers, Françoise Portaels, and Douglas S. Walsh

272.Buruli Ulcer (Mycobacterium ulcerans Infection), Wayne M. Meyers, FrançoisePortaels, and Douglas S. Walsh

273.Mycoplasma Infections, Julia A. McMillan

274. Meisseriagonorrhoeae, Mary Allen Staat

275. NeisseriaMeningitidis, MicheleEstabrook

276. Nocardiosis, Mahed Abdel-Haq and Ashir Kumar

277. Pasteurellamultocida, Morven S. Edwards

278.Pertussis, BeverlyL. Connelly

279. Plague, GaryD. Overturf

280. Pneumococcal Infections, Sandra R. Arnold and P. JoanChesney

281.Rat-Bite Fever, Lorry G. Rubin

282. Relapsing Fever, Dennis L. Murray

283. Salmonella, Shigella, and Escherichia coli, Andrew T. Pavia

284.Staphylococcus Infections, Beverly L. Connelly

285. Streptococcal Group A Infections, Mark R. Schleiss and Edward L.Kaplan

286. Group B Streptococcal Infections, Morven S. Edwards

287.Nongroup A or B Streptococci, Dwight A. Powell

288. Syphillis, Mary Allen Staat

289. Tetanus, GaryD. Overturf

290. Q Fever, GordonE. Schutze

291. Tularemia, Jessica Nichols, Stephanie H.Stovall, and Richard F. Jacobs

292. Ureaplasmaurealyticum Infections, Tara M. Randis and Adam J. Ratner

293. Yersiniaenterocolitica Infections, Basim I. Asmir

294.Rickettsial Infections, Gordon E. Schutze

Part 6: Fungal Infections

295. Aspergillosis, Deborah Lehman

296.Blastomycosis, Dwight A. Powell

297.Candida, KatherineM. Knapp

298.Coccidioidomycosis, Mark R. Schleiss

299.Cryptococcosis, Deborah Lehman

300.Histoplasmosis, Martin B. Kleiman

301. Malasseziafurfur, Dwight A. Powell

302.Microsporidiosis, Luis F. Barroso II and Richard L.Guerrant

303.Sporotrichosis, Donna M. Nobile and Martin B.Kleiman

304.Zygomycosis (Mucormycosis), Rebecca C. Brady

Part 7: Viral Infections

305. Arboviruses, Jason Brophy and Elizabeth LeeFord-Jones

306.Enterovirus Infections, José R. Romero

307.Hemorrhagic Fevers, Eileen C. Farnon, Thomas G.Ksiazek, and Ali S. Khan

308.Viral Hepatitis, Henry Pollack and William Borkowsky

309.Herpes Simplex Virus Infections, David K. Hong and Charles G. Prober

310.Cytomegalovirus, Mark R. Schleiss

311.Epstein-Barr Virus (EBV) Mononucleosis, W. Garrett Hunt and Michael T.Brady

312. Human Herpesviruses 6 and 7, Mark R. Schleiss

313. Human Herpesvirus 8, Mark R. Schleiss

314. Varicella-Zoster Virus Infections, Sophie Hambleton

315. Human Immunodeficiency Virus Type 1Infection, Michael T. Brady

316. Measles, WilliamJ. Moss and Samuel L. Katz

317.MolluscumContagiosum, Magdalene A. Dohil and Lawrence F.Eichenfield

318.Mumps, DennisL. Murray

319. Human Parvovirus, Peggy Sue Weintrub

320. Rubella, MariaJevitz Patterson

321.Rabies, PeggySue Weintrub

322. Smallpox, AnneA. Gershon

Part 8: Parasitic Infections--Nematodes

323. Antiparasitic Therapy, Melissa Hold and Michael Cappello

324.Ascariasis, John S. Schieffelin and Richard A.Oberhelman

325.Baylisascariasis, John S. Schieffelin and Richard A.Oberhelman

326.Dracunculiasis, John S. Schieffelin and Richard A.Oberhelman

327.Enterobiasis (Pinworm), Richard A. Oberhelman

328.Lymphatic Filariasis and Onchocerciasis, Doran L. Fink and Thomas B. Nutman

329.Hookworm, MelissaHeld and Michael Cappello

330.Strongyloidiasis, Richard A. Oberhelman

331. Toxocariasis (Visceral and Ocular LarvaMigrans), Richard A.Oberhelman and Peter J. Hotez

332.Trichinosis, Richard A. Oberhelman

333.Trichuriasis, John S. Schieffelin and Richard A.Oberhelman

334.Anasakiasis and Angiostrongyliasis, Richard A. Oberhelman

Part 9: Parasitic Infections--Trematodes

335. Foodborne Trematodiasis andSchistosomiasis, Jennifer Keiserand JürgUtzinger

336.Diphyllobothriasis, Hector H. Garcia and Robert H.Gillman

337.Dipylidiasis, Hector H. Garcia and Robert H.Gilman

338.Echinococcosis, Hector H. Garcia, Saul Santivanez,and Robert H. Gilman

339.Hymenolepiasis, Hector H. Garcia and Robert H.Gilman

340.Taeniasis and Cysticercosis, Gary D. Overturf

Part 10: Parasitic Infections--Protozoa

341. Amebiasis, IbneKarim M. Ali and William A.Petri, Jr.

342. Babesiosis, Peter J. Krause

343.Balantidiasis, Eduardo Ortega-Barria and ElidiaDominguez

344. Blastocytishominis

345.Cryptosporidiosis, Luis F. Barroso, II, and Richard L.Guerrant

346.Cyclosporiasis, CirleAlcantara Warren and RichardL. Guerrant

347.Dientamoebiasis, Dennis L. Murray

348. Free-Living Amebic Infections, IbneKarim M. Ali and William A.Petri, Jr.

349. Giardiasis, Richard A. Oberhalman

350.Isosporiasis, CirleAlcantara Warren

351. Leishmaniasis, Eduardo Ortega-Barria and Luz I.Romero

352.Malaria, ChandyC. John

353. Pneumocystis Pneumonia, Walter T. Hughes

354. Toxoplasmosis, Nicole M. A. Le Saux

355.Trypanosomiases, Eduardo Ortega-Barria

SECTION 18: DISORDERS OF THE SKIN

Section Editors: Beth Drolet and Sheila S.Galbraith

356. Functional Overview, Brook E. Tlougan and Amy S. Paller

357. Neonatal Dermatology, Sheila S. Galbraith

358. Disorders of the Epidermis, Kristen E. Holland

359.Disorders of the Dermis and SubcutaneousTissue, Anita N. Haggstrom

360.Genetics Disorders of the Skin, Brook E. Tlougan and Amy S. Paller

361.Melanocytic Lesions and Disorders ofPigmentation, Julie V.Schaffer and Seth J. Orlov

362.Immunologic Diseases, Julie Prendiville

363.Neoplastic and Proliferative Disorders, Victoria R. Barrio and Lawrence F.Eichenfield

364.Vascular Tumors and Malformations, Ilona J. Frieden and Sheilagh M.Maguiness

365.Acne and Other Disorders of thePilosebaceous Unit, Sara W.Dill and Bari B. Cunningham

366.Disorders of Nails, Liborka Kos

367.Skin Infections and Exanthems, Jane S. Bellet and Anthony J.Mancini

368. Infestations, Denise W. Metry

SECTION 19: DISORDERS OF THE EAR, NOSE, ANDTHROAT

Section Editor: Joseph Kerschner

369. The Ear, JohnH. Greinwald Jr., Margaret A. Kenna, and Blake C. Papsin

370.Nose and Sinus, Ellen S. Deutsch and Cecille G.Sulman

371.The Pharynx and Upper Airway, Marshall E. Smith

372.The Head, Face, and Neck, Craig S. Derkay and Michael J.Cunningham

373. Head and Neck Masses, David E. Tunkel and Jonathan A.Perkins

SECTION 20: DISORDERS OF THE ORAL CAVITY

Section Editors: Howard L. Needleman andStephen Shusterman

374. Dental Caries, Man Wai Ng and Isabelle I. Chase

375.Dental Emergency Care, Howard L. Needleman and Brian Grove

376.Dental Occlusion and Its Management, Richard Bruun andSivabalanVasudavan

377.Periodontal and Gingival Health andDiseases, Nadeem Y. Karimbuxand David M. Kim

378.Oral Pathology, Andrew L. Sonis and Brian Grove

379.Temporomandibular Joint Disorders, Bonnie L. Padwa

380. Behavioral Treatment Options in PediatricDentistry, Stephen Shustermanand Linda P. Nelson

SECTION 21: DISORDERS OF THE GASTROINTESTINALTRACT

Section Editor: Colin D. Rudolph

Part 1: Presenting Signs and Symptoms

381. Normal Structure and Function of theGastrointestinal Tract, AlanN. Mayer

382. Approach to the Child with Acute, Chronic,or Cyclic Vomiting, B.U.K. Li

383. Acute Abdominal Pain, J. Craig Egan, John J. Aiken, andColin D. Rudolph

384.Chronic Abdominal Pain, Adrian Miranda

385.Diarrhea, RicardoA. Caicedo and Ivor D. Hill

386.Constipation and Fecal Incontinence, Manu R. Sood

387. Upper and Lower Gastrointestinal Bleeding, Richard J. Noel

388. Abdominal Masses, John C. Densmore and Keith T.Oldham

389.Gastrointestinal Obstruction, PradeepNazarey and Thomas T. Sato

390. Protein-Losing Enteropathy, Richard J. Noel

391. Gastrointestinal Disorders Associated withImmunodeficiency, Richard J.Noel

Part 2: Esophageal Disorders

392. Anatomic Disorders of the Esophagus, Dave R. Lal

393.Disorders of Esophageal Motility, Neelesh A. Tipnis

394.Gastroesophageal Reflux and Other Causes ofEsophageal Inflammation, ColinD. Rudolph

395. Other Esophageal Disorders, Tonya Adamiak and Colin D. Rudolph

Part 3: Congenital and Anatomic Disorders ofthe Stomach and Intestine

396. Abdominal Wall Defects, Danielle B. Peterson and MarjorieJ. Arca

397.Malrotation and Volvulus, John J. Aiken

398. Infantile Hypertrophic Pyloric Stenosis, Rachel Adams Greenup and Casey M.Calkins

399.Congenital Atresias, Stenosis, and Webs, Andrea Winthrop and Jill Whitehouse

400.Microgastria and Gastric Perforation, Andrea Winthrop and Jill Whitehouse

401.Duplications and Cysts, Denise B. Klinkner and David M.Gourlay

402.Omphalo-Mesenteric Duct Remnants, Denise B. Klinkner and David M.Gourlay

403.Meconium Diseases of Infancy and DistalIntestinal Obstruction Syndrome, PradeepNazareyand Thomas T. Sato

404.Intussusception, John C. Densmore and Dave R. Lal

405.Inguinal and Other Hernias, John J. Aiken

406. Superior Mesenteric Artery Syndrome, Vincent F. Biank

407. Motor Disorders of the Stomach, SmallBowel, and Colon, Manu R. Soodand Casey M. Calkins

Part 4: Disorders of Digestion and Absorption

408. Disorders of Digestion and Absorption, Ivor D. Hill and Ricardo A. Caicedo

Part 5: Disorders of the Stomach andIntestine

409. Inflammatory Disorders of the Stomach, RanjanDohil and Eric Hassall

410.Inflammatory Bowel Disease, Michael C. Stephens,SubraKugathasan, and Thomas T. Sato

411.Allergic andEosinophilicGastroenteropathies, B.U.K.Li

412.Vascular, Systemic, and Other DisordersAffecting the Gastrointestinal TractGrzegorzTelega, Vince F. Biank, andB.U.K. Li

413.Acute Appendicitis, Typhlitis, and ChronicAppendicitis, J. Craig Eganand John J. Aiken

414.Polyps and Tumors of the GastrointestinalTract, Steve H. Erdman andEdward J. Hoffenberg

415.Congenital Anomalies of the Anorectum, Casey M. Calkins and Manu R. Sood

416. Other Anorectal Disorders, Judith M. Sondheimer

Part 6: The Exocrine Pancreas

417. Disorders of the Exocrine Pancreas, Steven L. Werlin

SECTION 22: DISORDERS OF THE LIVER ANDBILIARY TRACT

Section Editor: Saul Karpen

418. Structure and Function of the Liver, Jonathan E. Teitelbaum

419. Evaluation of the Infant and Child withLiver Disease, Robert H.Squires, Jr.

420. Autoimmune Disorders of the Liver, Nada Yazigi

421.Metabolic and Genetic Disorders of theLiver, Frederick J. Suchy

422.Drug, Toxin, and TPN Liver Disease, Christopher D. Jolley, Regino P.González-Peralta, and Beth A. Carter

423.The Liver in Systemic Disease, Maureen M. Jonas

424. Acute Liver Failure, Vicky Lee Ng

425. End-Stage Liver Disease, Vicky Lee Ng

426.Other Disorders of the Liver, Stephanie Abrams

427. The Biliary Tract, Colin D. Rudolph, GregorzTelega,Vincent Biank, and Douglas S. Fishman

SECTION 23: DISORDERS OF THE BLOOD

Section Editor: George R. Buchanan

Part 1: Principles of Blood Disorders

428. Approach to Suspected HematologicDisorders, George R. Buchanan

429. Hematopoeisis, Charles T. Quinn

Part 2: Disorders of Red Blood Cells andAnemia

430. Anemia, MatthewM. Heeney

431. Iron Deficiency, Matthew M. Heeney

432. Anemia Due to Diminished Red Blood CellProduction, Zora R. Rogers

433.Hemolytic Anemia, Amber Mayfield Yates and Russell E.Ware

434.Hemoglobinopathies, Charles T. Quinn

Part 3: Disorders of Coagulation andPlatelets

435. Normal and Abnormal Coagulation, Janna M. Journeycake, Anthony K. C.Chan, and Janet Yang

436.Inherited Bleeding Disorders, Amy L. Dunn, Shannon L. Meeks, andThomas C. Abshire

437.Acquired Coagulation Disorders, Guy Young

438.Diagnosis and Management of Thrombosis, Janna M. Journeycake and Anthony K.C. Chan

439. Disorders of Platelets, Cindy E. Neunert and Donald L. Yee

Part 4: Disorders of the Spleen and LymphNodes

440. The Spleen and Lymph Nodes, Shelley E. Crary

Part 5: Disorders of White Blood Cells,

441. Disorders of Granulocytes, R. Alexander Blackwood and LawrenceA. Boxer

Part 6: Principles of Transfusion

442. Transfusion Medicine, Cassandra D. Josephson

SECTION 24: NEOPLASTIC DISORDERS

Section Editor: Robert J. Arceci

Part 1: Principles of Oncology

443. Cancer Genetics and Biology, David Malkin

444. Epidemiology of Childhood Cancer, Louise Parker

445.Chemotherapy and Radiation Therapy, Peter C. Adamson and Larry E. Kun

446.Clinical Trials in Pediatric Oncology, Malcolm A. Smith and Gregory H.Reaman

447.Neonatal Oncology, Sheila Weitzman, Yaron Finkelstein,and Robert J. Arceci

448. Cancer Survivorship and Recommendations forFollow-Up, Smita Bhatia andAnna Meadows

Part 2: Hematologic Malignancies

449. Acute Lymphoblastic Leukemia, James B. Nachman

450. Myeloid Malignancies, SoheilMeshinchi, Robert J. Arceci,and Howard J. Weinstein

451. Non-Hodgkin Lymphoma, Mitchell S. Cairo and Thomas G.Gross

452. Hodgkin Lymphoma, Melissa M. Hudson and Tanya M.Trippett

Part 3: Solid Tumors

453. Osteosarcoma, Richard Gorlick and Paul A. Meyers

454.Ewing Sarcoma and Primitive NeuroectodermalTumor, Crystal L. Mackall andJeffrey A. Toretsky

455.Rhabdomyosarcoma, Douglas S. Hawkins and Frederic G.Barr

456.Renal Tumors, Elizabeth Mullen

457.Neuroblastoma, Michael D. Hogarty and Garrett M.Brodeur

458.Malignant Liver Tumors, Gail E. Tomlinson and Howard M.Katzenstein

459.Germ Cell Tumors, Thomas A. Olson

460.Brain Tumors and Spinal Tumors, Kenneth J. Cohen and Ian F. Pollack

461.Retinoblastoma, Rima F. Jubran and Anna T. Meadows

462. Vascular Neoplasms, Denise M. Adams and Michael E.Kelly

Part 4: Mononuclear Phagocytic SystemDisorders

463. Histiocytic Disorders, R. Maarten Egeler, Robert J.Arceci, and Jan-IngeHenter

SECTION 25: DISORDERS OF THE KIDNEY ANDURINARY TRACT

Section Editor: Norman D. Rosenblum

Part 1: Principles of Nephrology

464. Renal Morphogenesis, Sunder Sims-Lucas and Carlton M.Bates

465.Development of Renal Function, Tino D. Piscione

466.Fluid, Electrolyte, and Acid-Base Disorders, ManjulaGowrishankar

467. Diagnostic Approach to Renal Disease, John W. Foreman

Part 2: Abnormalities of the Kidney andUrinary Tract

468. Kidney or Urinary Tract Disorders, John W. Foreman

469.Renal Malformations, Norman D. Rosenblum

470.Cystic Diseases of the Kidney, Friedhelm Hildebrandt

471. Acute Renal Failure, Prasad Devarajan

472. Glomerular Diseases, Allison A. Eddy

473. Hereditary Glomerulopathies, Clifford E. Kashtan

474. Renal Tubular Disorders, Michel Baum

475. Urinary Tract Stone Diseases, Valerie Langlois

476. Urologic Abnormalities of the GenitourinaryTract, Luis H.P. Braga andDarius J. Bägli

Part 3: Chronic Kidney Disease

477. Chronic Kidney Disease, Denis F. Geary

478. Chronic Dialysis, Stuart L. Goldstein

479. Systemic Hypertension, Craig W. Belsha and Joseph T. Flynn

SECTION 26: DISORDERS OF THE CARDIOVASCULARSYSTEM

Section Editors: Julien I. E. Hoffman andDavid Teitel

Part 1: Principles of Cardiology

480. Development of the Cardiovascular System, Deepak Srivastava

481. Genetics of Heart Disease, Kathleen M. Ruppel

Part 2: Approach to the Patient with CardiovascularDisease

482. Fetal Cardiology, Lisa K. Hornberger and Jean Trines

483.Neonate and Infant with CardiovascularDisease, David Teitel

484.Congenital Heart Disease, Julien I.E. Hoffman

485.Arrhythmias, George F. Van Hare and LouisLarrick

486. Child and Adolescent with CardiovascularDisease, Howard P. Gutgeselland George M. McDaniel

Part 3: Acquired Cardiovascular Disease

487. Cardiac Tumors, Julien I.E. Hoffman

488.Kawasaki Disease, Mary Beth Son and Jane W. Newburger

489.Diseases of Myocardium, Jeffrey A. Towbin

490.Infective Endocarditis, Jane W. Newberger

491.Pericardial Diseases, Julien I.E. Hoffman

492. Pulmonary Hypertension, Julien I.E. Hoffman

Part 4: Diagnostic Tools in Heart Disease

493. Electrocardiography, George F. Van Hare

494.Radiologic Imaging, Alison Knauth Meadows and MichaelW. Dae

495.Echocardiography, Therasa A. Tacy

496. Cardiac Catherization, Phillip Moore

Part 5: Management of Patients withCardiovascular Disease

497. Heart Failure, Robert E. Shaddy andChitraRavishankar

498.The Patient with Single Ventricle, Jacqueline Kreutzer

499. Interventional Cardiology, Phillip Moore

500. Health Care Management, Mark Cocalis

501. Sudden Death, Julien I.E. Hoffman

SECTION 27: DISORDERS OF THE RESPIRATORYSYSTEM

Section Editor: Jay K. Kolls

Part 1: Principles of Pulmonology

502. Lung Growth in Infacy and Childhood, Richard L. Auten

503.Physiologic Basis of Pulmonary Function, Daniel J. Weiner

504.Global Burden of Respiratory Infections andMucosal Immunology of the Respiratory Tract, JayK. Kolls and Joseph P. Mizgerd

505.Clinical Presentation of RespiratoryIllness, Hans Pasterkamp

506. Tools for Diagnosis and Management ofRespiratory Disease, BeverlyNewman and Geoffrey Kurland

Part 2: Disorders of the Respiratory System

507. Congenital Disorders of the Lower Airwaysand Mediastinum, Andrew Bush

508.Disorders of Respiratory Control andSleep-Disordered Breathing, DavidGozal and Leila Kheirandish-Gozal

509. Sleep Disorders, HemantSawnani andNarongSimakajornboon

510. Disorders Causing Airway Obstruction, Shean J. Aujla and Jonathan E.Spahr

511. Aspiration Syndromes, Cori L. Daines

512. Asthma, GurjitK. Khurana Hershey

513.Bronchopulmonary Dysplasia, Timothy D. Murphy

514. Cystic Fibrosis, David M. Orenstein

515. Interstitial Lung Disease, Jennifer A. Rama and Leland L. Fan

516.Alpha-1 Antitrypsin Deficiency Lung Disease, Terence R. Flotte and ChristianMueller

517.Pulmonary Vasculitis Syndromes, Paul Rosen

518.Pulmonary AlviolarProteinosis, Bruce C. Trapnell and Lisa R. Young

519. Chest Wall and Respiratory MuscleDisorders, Jonathan D. Finder

SECTION 28: DISORDERS OF THE ENDOCRINE SYSTEM

Section Editors: Allen W. Root

520. Mechanisms of Hormone Action, AddaGrimberg and Linda A. DeMeglio

521.Disorders of the Anterior Pituitary Gland, Edward O. Reiter

522.Growth and Growth Impairment, Edward O. Reiter

523.Endocrine Abnormalities Causing GrowthImpairment, Edward O. Reiter

524. Tall Stature, Edward O. Reiter

525. Primary Disturbances in Water Hemeostasis, AbhinashSrivatsa and Joseph A.Majzoub

526. The Thyroid, Delbert A. Fisher

527. Hypothyroidism in the Infact, Delbert A. Fisher

528.Acquired Hypothyroidism in the Infant, Delbert A. Fisher

529.Hyperthyroidism, Delbert A. Fisher

530.Other Disorders of the Thyroid, Delbert A. Fisher

531. The Adrenal Cortex, Walter L. Miller

532. Evaluation of the Adrenal Function, Walter L. Miller

533.Genetic Lesions in Steroidogenesis, Walter L. Miller

534. Adrenal Insufficiency, Walter L. Miller

535. Adrenal Excess, Walter L. Miller

536. Glucocorticoid Therapy and Withdrawal, Walter L. Miller

537. Endocrine Neoplasia Syndromes, Steven D. Chernausek andConstantine A. Stratakis

538. Normal Human Sex Differentiation, Melvin M. Grumbach

539. Disorders of Sexual Development (DSD), Melvin M. Grumbach

540.Normal Pubertal Development, Dennis M. Styne and LeonnaCuttler

541.Abnormal Pubertal Development, Dennis M. Styne and LeonnaCuttler

542.Calcium, Phosphorus, and MagnesiumMetabolism, Allen W. Root

543.Disorders of Bone Formation, Allen W. Root

544.Diabetes Mellitus in Children andAdolescents, Arlan L.Rosenbloom

545. Endocrine Causes of Hypoglocemia, Andrea Kelly and Charles A. Stanley

SECTION 29: DISORDERS OF THE NERVOUS SYSTEM

Section Editors: Scott L. Pomeroy, Blaise F.D. Bourgeois, Basil T. Darras, Edward M. Kaye

Part 1: Principles of Neurology

546. Introduction to Neurology, Mustafa Sahin

547. Clinical Approach to Neurologic Disease, MaitreyiMazumbar

Part 2: Abnormal Development of the NervousSystem

548. Cranial Development Abnormalities, Omar Khwaja

549.Disturbances of the Neural Tube and SpineClosure, Omar Khwaja

550. Macrocephaly and Microcephaly: Approach andDifferential Diagnosis, NicoleUllrich

Part 3: Acute Deterioration of NeurologicFunction

551. Trauma to the Nervous System, Magdi M. Sobeih

552.Stroke and Cerebrovascular Disease, Michael J. Ravkin

553.Hydrocephalus and PseudotumorCerebri, Nicole Ullrich

554.Cerebral Palsy and Static Encephalopathies, Robert S. Rust and David K. Urion

555.Infections of the Central Nervous System, Kiran P. Maski and Nicole Ullrich

556. Immune- and Inflammatory-Mediated CentralNervous System Syndromes, MarkP. Gorman

Part 4: Epilepsy

557. Epidemiology of Epilepsy, SeizureClassification, Epilepsy Syndromes, MarkH. Libenson and Ann M. Bergin

558.Etiologies of Epilepsies, Annapurna Poduri

559.Febrile Seizures, Masanori Takeoka

560.Evaluation of New Onset Seizures, Alexander Rotenberg

561. Status Epilepticus, Alexander Rotenberg

562. Antiepileptic Drug Therapy, Blaise F. D. Bougeois

563. Ketogenic Diet and Vagus Nerve StimulationTherapy, Ann M. Bergin

564. Pediatric Epilepsy Surgery, Dean P. Sarco

Part 5: Paroxysmal Disorders

565. Migraine and Headache Disorders, Alyssa Ann LeBel and Ann Minster

566. Movement Disorders, Tics, and TouretteSyndrome, Diana Apetauerova

567. Other Paroxysmal Disorders, Sanjeev V. Kothare

Part 6: Disorders of Strength, Tone, andSensation

568. General Evaluation of Strength, Tone, andSensation, Peter B. Kang andBasil T. Darras

569. The Hypotonic Infant, Basil T. Darras

570. Peripheral Nerve Disorders and AnteriorHorn Cell Diseases, Peter B.KangH.Royden Jones

572. Myopathies, Basil T.Darras

Part 7: Developmental Delay and Regression

573. Neurologic Aspects of Disorders of Metal Metabolism, Cecilia Mellado and Mustafa Sahin

574.Lysosomal Storage Disorders, IrinaA. Anselm

575.Rett Syndrome (MECP2-related disorders), Cecilia Mellado and Mustafa Sahin

576.Leukoencephalopathies, MarkP. Gorman

577. Neurotransmitter Disorders, ErikaF. Augustine and Annapurna Poduri

578.Phakomatoses, MustafaSahin

SECTION 30: DISORDERS OF THE EYES

Section Editor: Alex V. Levin

Part 1: General Principles

579. Anatomy and Physiology of the Eye and Ocular System, Monte A. Del Monte

580.Office Evaluation of the Eyes, GreggT. Lueder

581.Special Tests of the Eyes, DanielJ. Karr and Alex V. Levin

582. International Pediatric Ophthalmology, SherwinJ. Isenberg and Leonard Apt

Part 2: Disorders of the Eye

583. Eye Emergencies and Trauma, DanielJ. Karr and Alex V. Levin

584.Visual Impairment in Childhood, DavidS. Walton

585.Amblyopia, Anthony G.Quinn and Alex V. Levin

586.Strabismus, Robert W.Enzenauer, Mary Ellen Hoehn, and Monte A. Del Monte

587.The Eye in Child Abuse, AlexV. Levin

588. Red Eye, Anthony G. Quinn

589. Lid and Lacrimal System Disorders, GreggT. Lueder

590.Anterior Segment Disorders, DavidS. Walton

591.Retinopathy of Prematurity, EarlA. Palmer and Irene Hsu-Dresden

592.Genetic Eye Diseases, J.Bronwyn Bateman, John Roarty, Christina L. Butera, and Alex V. Levin

593. Optic Nerve Disorders, JohnRoarty

Index