有机合成百题精解

第一章 解答有机合成题的基础知识准备················································································ 1

一、烃类和简单杂环的官能团化····························································································· 1

二、官能团的转换················································································································ 6

三、复习和熟练掌握碳链的增长方法······················································································ 9

四、熟悉一些重要的重排反应······························································································ 10

五、掌握碳碳键的构建方法·································································································· 10

六、掌握化学键的切断与逆合成分析法················································································· 10

七、熟悉按照化学键异裂方式切断后的常见合成子及其对应的等价物······································· 10

八、逆合成分析切断法的技巧······························································································ 11

九、一条理想的合成路线的确定需要把握的几点···································································· 11

第二章 有机化合物常见增长和缩短碳链的方法····································································· 12

第一节 增长碳链的方法····································································································· 12

一、增加一个碳原子的常见方法··························································································· 12

二、增加两个碳原子的常见方法··························································································· 16

三、增加三个碳原子的常见方法··························································································· 19

四、增加四个碳原子的常见方法··························································································· 22

五、碳链倍增法·················································································································· 22

第二节 缩短碳链的方法····································································································· 24

一、减少一个碳原子的常见方法··························································································· 24

二、烯烃通过氧化断键减少一个或多个碳的方法···································································· 25

第三章 有机合成练习题题解······························································································· 26

参考文献·························································································································· 238