Williams血液学（第9版 英文版）

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目ContributorsPreface

PART

IClinical

Evaluationof

the

PatientPARTII

TheOrganization

of

the

LymphohematopoieticTissuesPARTIII

EpochalHematologyPARTIV

Molecular

and

CellularHematologyPARTV

TherapeuticPrinciplesPARTVI

The

ErythrocytePARTVII

Neutrophils,Eosinophils,Basophils,

and

MastCellsPARTVIII

Monocytes

and

MacrophagesPARTIX

Lymphocytes

and

Plasma

CellsPARTX

MalignantMyeloid

DiseasesPARTXI

MalignantLymphoid

DiseasesPARTXII

Hemostasis

andThrombosisPARTXIII

Transfusion

MedicineIndex

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.xxi

PART

IClinicalEvaluation

of

the

Patient1.InitialApproachto

the

Patient:HistoryandPhysicalExamination2.Examinationof

Blood

Cells3.ExaminationofTheMarrow4.ConsultativeHematologyPART

IITheOrganization

of

the

LymphohematopoieticTissues5.Structureof

the

Marrowand

the

HematopoieticMicroenvironment6.The

Organizationand

StructureofLymphoidTissuesPART

IIIEpochal

Hematology7.Hematologyof

the

FetusandNewborn8.HematologyduringPregnancy9.Hematology

in

OlderPersons

PART

IVMolecular

and

CellularHematology10.Genetic

PrinciplesandMolecular

Biology11.Genomics12.Epigenetics13.Cytogeneticsand

Genetic

Abnormalities14.MetabolismofHematologicNeoplastic

Cells15.ApoptosisMechanisms:Relevanceto

the

HematopoieticSystem16.Cell-CycleRegulationandHematologicDisorders17.SignalTransductionPathways18.HematopoieticStem

Cells,

Progenitors,andCytokines19.TheInflammatoryResponse20.InnateImmunity21.Dendritic

Cells

andAdaptiveImmunityPARTVTherapeuticPrinciples22.PharmacologyandToxicityofAntineoplastic

Drugs23.Hematopoietic

Cell

Transplantation24.Treatment

of

InfectionsinTheImmunocompromisedHost25.AntithromboticTherapy26.Immune

Cell

Therapy27.VaccineTherapy28.TherapeuticApheresis:Indications,Efficacy,andComplications29.Gene

TherapyforHematologicDiseases30.RegenerativeMedicine:MultipotentialCellTherapy

forTissueRepairPARTVIThe

Erythrocyte31.StructureandCompositionof

the

Erythrocyte32.Erythropoiesis33.Erythrocyte

Turnover34.ClinicalManifestations

and

Classification

ofErythrocyteDisorders35.AplasticAnemia:Acquiredand

Inherited.36.

Pure

Red

Cell

Aplasia

Anemia

ofChronicDisease38.

The

CongenitalDyserythropoieticAnemias39.

ParoxysmalNocturnal

Hemoglobinuria40.

ParoxysmalNocturnalHemoglobinuria41.

Folate,Cobalamin,andMegaloblasticAnemias42.IronMetabolism43.Iron

Deficiency

andOverload44.

AnemiaResulting

fromOtherNutritionalDeficiencies45.

AnemiaAssociatedwithMarrowInfiltration46.

Erythrocyte

MembraneDisorders47.

Erythrocyte

Enzyme

Disorders48.

TheThalassemias:Disorders

of

GlobinSynthesis49.

DisordersofHemoglobinStructure:Sickle

CellAnemiaandRelatedAbnormalities50.

Methemoglobinemiaand

Other

Dyshemoglobinemias51.

FragmentationHemolyticAnemia52.

Erythrocyte

Disordersas

a

ResultofChemicalandPhysicalAgents53.

HemolyticAnemiaResultingfromInfectionswithMicroorganisms54.

HemolyticAnemiaResultingfromImmuneInjury55.

AlloimmuneHemolytic

Disease

of

the

FetusandNewborn56.

HypersplenismandHyposplenism57.

Primary

and

Secondary

Erythrocytoses58.ThePorphyrias59.PolyclonalandHereditarySideroblasticAnemiasPARTVIINeutrophils,Eosinophils,Basophils,

and

Mast

Cells60.

StructureandCompositionofNeutrophils,Eosinophils,andBasophils61.

Production,Distribution,andFateofNeutrophils62.

EosinophilsandRelatedDisorders63.

Basophils,Mast

Cells,

andRelatedDisorders64.

ClassificationandClinical

ManifestationsofNeutrophilDisorders65.

NeutropeniaandNeutrophilia66.

DisordersofNeutrophilFunctionPARTVIIIMonocytes

and

Macrophages67.

Structure,Receptors,andFunctionsofMonocytesandMacrophages68.

Production,Distribution,andActivationofMonocytesandMacrophages69.

ClassificationandClinicalManifestationsof

DisordersofMonocytesandMacrophages70.

MonocytosisandMonocytopenia71.

InflammatoryandMalignantHistiocytosis72.

Gaucher

Disease

andRelatedLysosomalStorageDiseases73.

PART

IXLymphocytes

and

Plasma

Cells73.TheStructureofLymphocytes

andPlasma

Cells74.LymphopoiesisFunctionsof

B

LymphocytesandPlasmaCells

inImmunoglobulinProduction75.

Functionsof

T

Lymphocytes:T-CellReceptorsforAntigen76.

FunctionsofNaturalKiller

Cells77.

ClassificationandClinical

ManifestationsofLymphocyteandPlasma

Cell

Disorders79.LymphocytosisandLymphocytopenia80.ImmunodeficiencyDiseases81.HematologicManifestationsofAcquiredImmunodeficiencySyndrome82.MononucleosisSyndromesPART

XMalignantMyeloid

Diseases83.Classificationand

ClinicalManifestationsoftheClonalMyeloidDisorders84.PolycythemiaVera85.EssentialThrombocythemia86.Primary

Myelofibrosis87.MyelodysplasticSyndromes88.AcuteMyelogenousLeukemia89.ChronicMyelogenousLeukemiaandRelatedDisordersPART

XIMalignantLymphoid

Diseases90.ClassificationofMalignantLymphoid

Disorders91.AcuteLymphoblasticLeukemia92.ChronicLymphocyticLeukemia93.Hairy

Cell

Leukemia94.LargeGranularLymphocyticLeukemia95.General

ConsiderationsforLymphomas:Epidemiology,Etiology,Heterogeneity,and

Primary

ExtranodalDisease96.PathologyofLymphomas.97.HodgkinLymphoma98.Diffuse

Large

B-Cell

Lymphoma

andRelated

Diseases99.FollicularLymphoma100.Mantle

Cell

Lymphoma101.MarginalZone

B-Cell

Lymphomas102.BurkittLymphoma103.CutaneousT-CellLymphoma(MycosisFungoidesandSézarySyndrome)104.MatureT-CellandNaturalKiller

Cell

Lymphomas105.Plasma

Cell

Neoplasms:General

Considerations106.EssentialMonoclonalGammopathy107.Myeloma.108.ImmunoglobulinLight-ChainAmyloidosis109.Macroglobulinemia.110.Heavy-Chain

DiseasePART

XIIHemostasis

andThrombosis111.MegakaryopoiesisandThrombopoiesis112.PlateletMorphology,Biochemistry,and

Function113.Molecular

Biology

andBiochemistryof

theCoagulationFactorsandPathwaysofHemostasis114.ControlofCoagulationReactions115.VascularFunction

in

Hemostasis116.Classification,Clinical

Manifestations,

andEvaluationofDisordersofHemostasis117.Thrombocytopenia118.Heparin-InducedThrombocytopenia119.ReactiveThrombocytosis120.HereditaryQualitativePlateletDisorders121.AcquiredQualitativePlateletDisorders122.TheVascularPurpuras123.

Hemophilia

A

andHemophilia

B124.

InheritedDeficiencies

ofCoagulation

FactorsII,V,V

VIII,

VII,

X,

XI,

and

XII125.Hereditary

FibrinogenAbnormalities126.von

WillebrandDisease127.

Antibody-MediatedCoagulation

FactorDeficiencies128.

HemostaticAlterations

in

Liver

Disease

andLiverTransplantation129.

DisseminatedIntravascularCoagulation130.HereditaryThrombophilia131.

The

AntiphospholipidSyndrome132.

ThromboticMicroangiopathies133.VenousThrombosis134.

Atherothrombosis:

Disease

Initiation,Progression,andTreatment135.

FibrinolysisandThrombolysisPART

XIIITransfusion

Medicine136.

Erythrocyte

AntigensandAntibodies137.

Human

Leukocyte

andPlateletAntigens138.

Blood

Procurementand

Red

Cell

Transfusion139.

Preservationand

Clinical

UseofPlateletsIndex