癌症基因治疗学：英文版

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preface

partⅠ vectors for gene therapr of cancer

1.retroviral vector design for cancer gene therapy

2.noninfections gene transfer and expression systems for cancer gene therapy

3.parvovirus vectors for the gene therapy of cancer

4.antibody-targeted gene therapy

5.ribozymes in cancer gene therapy

6.the advent of lentiviral vectors:prospects for cancer therapy

part Ⅱ immune targetied gene therapy

7.immunologic targets for the gene therapy of cancer

part Ⅱa vaccine strategies

8.development of eqitope-specific immunotherapies for human malignancies and premalignant lesions expressing mutated ras genes

part Ⅱb dendritic cell-based gene therapy

9.introduction to dendritic cells

10.dna and dendritic cell-based genetic immunization against cancer

11.rna-transfected dendritic cells as immunogens

part Ⅱc cytokines and co-factors

12.in situ immune modulation using recombinatnt vaccinia virus vectors:preclinical studies to clinical implementation

13.the use of particle-mediated gene transfer of immunotherapy of cance

part Ⅱd genetically modified effector cells for immune-based immunotherapy

14.applications of gene transfer in the adoptive immunotherapy of cancer

15.update on the use of genetically modified hematoppietic stem cells for cancer therapy

part Ⅲ oncogene-targeted gene therapy

16.clinical applications of tumor-suppressor gene therapy

17.cancer gene therapy with tumor supperssor genes involved in cell-cycle control

18.cancer gene therapy with the p53 tumor suppressor gene

19.antisense downregulation of the apoptosis-related bcl-2and bcl-xl proteins:a new approach to cancer therapy

20.gene therpy for chronic myelogenous leukemia

part Ⅳ manulation of drug resistance mechanisms by gene therary

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part Ⅴ anti-aniogenesis and pro-aportotic gene therapy

part Ⅵ prodrug activation strategies for gene therapy of cancer

index